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A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability
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Generation of human induced pluripotent stem cells (EURACi001-A, EURACi002-A, EURACi003-A) from peripheral blood mononuclear cells of three patients carrying mutations in the CAV3 gene.
Stem Cell Research
Volume 27, March 2018, Pages 25-29. doi: 10.1016/j.scr.2017.12.012.
Meraviglia V, Benzoni P, Landi S, Murano C, Langione M, Motta BM, Baratto S, Silipigni R, Di Segni M, Pramstaller PP, DiFrancesco D, Gazzerro E, Barbuti A, Rossini A.
Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation.
Transl Res. 2018 Feb;192:54-67. doi: 10.1016/j.trsl.2017.11.003
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Structure-guided design of a cell penetrating peptide preventing cAMP modulation of HCN channels
bioRxiv, 253096 doi: https://doi.org/10.1101/253096
This article is a preprint and has not been peer-reviewed
Anna Moroni, Andrea Saponaro, Francesca Cantini, Alessandro Porro, Annalisa Bucchi, Dario DiFrancesco, Vincenzo Maione, Chiara Donadoni, Bianca Introini, Pietro Mesirca, Matteo E. Mangoni, Gerhard Thiel, Lucia Banci, Bina Santoro
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A Traditional Chinese Medicine Drug (TMYX) Controls Heart Rate by Modulation of the Pacemaker (F) Channels
Biophysical Journal, Volume 112, Issue 3, Supplement 1, p412a, 3 February 2017. DOI: 10.1016/j.bpj.2016.11.2565
Manuel Paina, Chiara Piantoni, Luca Carnevali, Anthony Frosio, Annalisa Bucchi, Andrea Barbuti, Liu Sheng, Wang Yanyan, Yi Wang, Dario DiFrancesco, Mirko Baruscotti
HCN3 Channel Expression in Human Leukocytes
Biophysical Journal, Volume 112, Issue 3, Supplement 1, p415a, 3 February 2017. doi: 10.1016/j.bpj.2016.11.2224
Chiara Piantoni, Angelica Gualdoni, Claudia Bazzini, Raffaella Milanesi, Miryam Adelfio, Annalisa Bucchi, Andrea Barbuti, Matteo Pecchiari, Mirko Baruscotti, Dario DiFrancesco
A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia.
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INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model.
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