Stem Cell Research
Volume 27, March 2018, Pages 25-29. doi: 10.1016/j.scr.2017.12.012.
Meraviglia V, Benzoni P, Landi S, Murano C, Langione M, Motta BM, Baratto S, Silipigni R, Di Segni M, Pramstaller PP, DiFrancesco D, Gazzerro E, Barbuti A, Rossini A.
Preferential myofibroblast differentiation of cardiac mesenchymal progenitor cells in the presence of atrial fibrillation.
Transl Res. 2018 Feb;192:54-67. doi: 10.1016/j.trsl.2017.11.003
Gambini E, Perrucci GL, Bassetti B, Spaltro G, Campostrini G, Lionetti MC, Pilozzi A, Martinelli F, Faruggia A, DiFrancesco D, Barbuti A, Pompilio G.
Structure-guided design of a cell penetrating peptide preventing cAMP modulation of HCN channels
bioRxiv, 253096 doi: https://doi.org/10.1101/253096
This article is a preprint and has not been peer-reviewed
Anna Moroni, Andrea Saponaro, Francesca Cantini, Alessandro Porro, Annalisa Bucchi, Dario DiFrancesco, Vincenzo Maione, Chiara Donadoni, Bianca Introini, Pietro Mesirca, Matteo E. Mangoni, Gerhard Thiel, Lucia Banci, Bina Santoro
Mammalian γ2 AMPK regulates intrinsic heart rate.
Nat Commun. 2017 Nov 2;8(1):1258. doi: 10.1038/s41467-017-01342-5.
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H.
The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability.
Cardiovasc Res. 2017 Aug 1;113(10):1256-1265. doi: 10.1093/cvr/cvx122.
Campostrini G, Bonzanni M, Lissoni A, Bazzini C, Milanesi R, Vezzoli E, Francolini M, Baruscotti M, Bucchi A, Rivolta I, Fantini M, Severi S, Cappato R, Crotti L, J Schwartz P, DiFrancesco D, Barbuti A.
A Traditional Chinese Medicine Drug (TMYX) Controls Heart Rate by Modulation of the Pacemaker (F) Channels
Biophysical Journal, Volume 112, Issue 3, Supplement 1, p412a, 3 February 2017. DOI: 10.1016/j.bpj.2016.11.2565
Manuel Paina, Chiara Piantoni, Luca Carnevali, Anthony Frosio, Annalisa Bucchi, Andrea Barbuti, Liu Sheng, Wang Yanyan, Yi Wang, Dario DiFrancesco, Mirko Baruscotti
HCN3 Channel Expression in Human Leukocytes
Biophysical Journal, Volume 112, Issue 3, Supplement 1, p415a, 3 February 2017. doi: 10.1016/j.bpj.2016.11.2224
Chiara Piantoni, Angelica Gualdoni, Claudia Bazzini, Raffaella Milanesi, Miryam Adelfio, Annalisa Bucchi, Andrea Barbuti, Matteo Pecchiari, Mirko Baruscotti, Dario DiFrancesco
A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia.
Eur Heart J. 2017 Jan 21;38(4):280-288. doi: 10.1093/eurheartj/ehv582.
Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D.
Anacardic acid and thyroid hormone enhance cardiomyocytes production from undifferentiated mouse ES cells along functionally distinct pathways.
Endocrine. 2016 Sep;53(3):681-8. doi: 10.1007/s12020-015-0751-2. Epub 2015 Nov 7.
Re A, Nanni S, Aiello A, Granata S, Colussi C, Campostrini G, Spallotta F, Mattiussi S, Pantisano V, D'Angelo C, Biroccio A, Rossini A, Barbuti A, DiFrancesco D, Trimarchi F, Pontecorvi A, Gaetano C, Farsetti A.
Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function.
Pflugers Arch. 2016 Oct;468(10):1663-71. doi: 10.1007/s00424-016-1870-1. Epub 2016 Aug 23.
Biel S, Aquila M, Hertel B, Berthold A, Neumann T, DiFrancesco D, Moroni A, Thiel G, Kauferstein S.
Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If “funny” current.
J Interv Card Electrophysiol. 2016 Jun;46(1):19-28. doi: 10.1007/s10840-015-0097-y. Epub 2016 Jan 18.
Baruscotti M, Bianco E, Bucchi A, DiFrancesco D.
INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model.
Sci Rep. 2016 Apr 15;6:24515. doi: 10.1038/srep24515.
Benedetti L, Ghilardi A, Rottoli E, De Maglie M, Prosperi L, Perego C, Baruscotti M, Bucchi A, Del Giacco L, Francolini M.
Higher cardiogenic potential of iPSCs derived from cardiac versus skin stromal cells.
Front Biosci (Landmark Ed). 2016 Jan 1;21:719-43.
Meraviglia V, Wen J, Piacentini L, Campostrini G, Wang C, Florio MC, Azzimato V, Fassina L, Langes M, Wong J, Miragoli M, Gaetano C, Pompilio G, Barbuti A, DiFrancesco D, Mascalzoni D, Pramstaller PP, Colombo GI, Chen HS, Rossini A.
Cell-specific Dynamic Clamp analysis of the role of funny If current in cardiac pacemaking.
Prog Biophys Mol Biol. 2016 Jan;120(1-3):50-66. doi: 10.1016/j.pbiomolbio.2015.12.004. Epub 2015 Dec 21.
Ravagli E, Bucchi A, Bartolucci C, Paina M, Baruscotti M, DiFrancesco D, Severi S.
HCN4, Sinus Bradycardia and Atrial Fibrillation.
Arrhythm Electrophysiol Rev. 2015 May;4(1):9-13. doi: 10.15420/aer.2015.4.1.9. Epub 2015 Mar 15.
DiFrancesco D.