Endocrine. 2016 Sep;53(3):681-8. doi: 10.1007/s12020-015-0751-2. Epub 2015 Nov 7.
Re A, Nanni S, Aiello A, Granata S, Colussi C, Campostrini G, Spallotta F, Mattiussi S, Pantisano V, D'Angelo C, Biroccio A, Rossini A, Barbuti A, DiFrancesco D, Trimarchi F, Pontecorvi A, Gaetano C, Farsetti A.
HCN4, Sinus Bradycardia and Atrial Fibrillation.
Arrhythm Electrophysiol Rev. 2015 May;4(1):9-13. doi: 10.15420/aer.2015.4.1.9. Epub 2015 Mar 15.
DiFrancesco D.
Dysfunctional HCN ion channels in neurological diseases.
Front Cell Neurosci. 2015 Mar 10;6:174. doi: 10.3389/fncel.2015.00071. eCollection 2015.
DiFrancesco JC, DiFrancesco D.
LEONARDO DA VINCI AND THE ORIGIN OF SEMEN.
Notes Rec R Soc Lond. 2014 Dec 20;68(4):391-402.
Noble D, DiFrancesco D, Zancani D.
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat Chem Biol. 2014 Jun;10(6):457-62.
Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, Moroni A.
Exercise training reduces resting heart rate via downregulation of the funny channel HCN4.
Nat Commun. 2014 May 13;5:3775.
D'Souza A, Bucchi A, Johnsen AB, Logantha SJ, Monfredi O, Yanni J, Prehar S, Hart G, Cartwright E, Wisloff U, Dobryznski H, DiFrancesco D, Morris GM, Boyett MR.
The ‘funny’ side of sepsis.
J Physiol. 2014 Mar 15;592(6):1171.
Barbuti A, DiFrancesco D.
Multifactorial impact of channel beta-subunit gene mutation on automaticity.
J Cardiovasc Electrophysiol. 2013 Dec;24(12):E26-7.
Difrancesco D, Nawathe PA, Robinson RB.
Funny channel gene mutations associated with arrhythmias.
J Physiol. 2013 Sep 1;591(17):4117-24.
DiFrancesco D.
An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia.
J Cardiovasc Electrophysiol. 2013 Sep;24(9):1021-7.
Nawathe PA, Kryukova Y, Oren RV, Milanesi R, Clancy CE, Lu JT, Moss AJ, Difrancesco D, Robinson RB.
Embryonic stem cell-derived CD166+ precursors develop into fully functional sinoatrial-like cells.
Circ Res. 2013 Aug 2;113(4):389-98.
DiFrancesco D, Barbuti A.
Identification of the molecular site of ivabradine binding to HCN4 channels.
PLoS One. 2013;8(1):e53132.
Bucchi A, Baruscotti M, Nardini M, Barbuti A, Micheloni S, Bolognesi M, DiFrancesco D.
In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors.
PLoS One. 2012;7(12):e51694.
Vecellio M, Meraviglia V, Nanni S, Barbuti A, Scavone A, DiFrancesco D, Farsetti A, Pompilio G, Colombo GI, Capogrossi MC, Gaetano C, Rossini A.
Clinical efficacy of ivabradine in patients with inappropriate sinus tachycardia: a prospective, randomized, placebo-controlled, double-blind, crossover evaluation.
J Am Coll Cardiol. 2012 Oct 9;60(15):1323-9.
Cappato R, Castelvecchio S, Ricci C, Bianco E, Vitali-Serdoz L, Gnecchi-Ruscone T, Pittalis M, De Ambroggi L, Baruscotti M, Gaeta M, Furlanello F, Di Francesco D, Lupo PP.
An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation.
J Physiol. 2012 Sep 15;590(18):4483-99.
Severi S, Fantini M, Charawi LA, DiFrancesco D.
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