Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.

Nat Chem Biol. 2014 Jun;10(6):457-62.
Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, Moroni A.

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